Diterpenos tipo abietano isolados de Plectranthus barbatus Andrews
نویسندگان
چکیده
منابع مشابه
Antimicrobial activity of Plectranthus barbatus (Lamiacea)
Introduction The medicinal potential of plant is due to the presence of active principles, capable of producing several pharmacological effects such as analgesic, antiseptic agents, diuretics, expectorants, tranquilizers, digestive healing, emollients, anti-diarrhoeal, among others [1]. The deep cultural roots of the Brazilian population facilitated the permanence of the use of herbal medicine ...
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Plectranthus barbatus is a medicinal plant used to treat a wide range of disorders including seizure. However, the anticonvulsant activity of this plant has not been studied in depth. We therefore sought to evaluate the anticonvulsant activity of a hydroalcoholic extract of P. barbatus leaves on seizures induced by strychnine sulphate (2.0 mg/kg) and pilocarpine (600 mg/kg) in mice. The extract...
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O ácido traquilobânico (2) foi incubado com Rhizopus stolonifer, com o objetivo de se sintetizar novos derivados diterpênicos. Após vinte dias, quatro metabólitos foram extraídos, isolados e caracterizados, dos quais dois apresentaram-se hidroxilados nas posições 7β (3) e 17 (5). Dois derivados rearranjados também foram isolados, os ácidos ent-16β-hidroxi-caur-11-en-19-óico (4) e 9α,16β-diidrox...
متن کاملIn Vitro Antiprotozoal Activity of Abietane Diterpenoids Isolated from Plectranthus barbatus Andr.
Chromatographic separation of the n-hexane extract of the aerial part of Plectranthus barbatus led to the isolation of five abietane-type diterpenes: dehydroabietane (1); 5,6-didehydro-7-hydroxy-taxodone (2); taxodione (3); 20-deoxocarnosol (4) and 6α,11,12,-trihydroxy-7β,20-epoxy-8,11,13-abietatriene (5). The structures were determined using spectroscopic methods including one- and two-dimensi...
متن کاملPlectranthus barbatus: a review of phytochemistry, ethnobotanical uses and pharmacology - Part 1.
Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractive target for intensive chemical and pharmacological studies up to now. This re...
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ژورنال
عنوان ژورنال: Química Nova
سال: 2007
ISSN: 0100-4042
DOI: 10.1590/s0100-40422007000800016